18F-Fluciclovine Uptake in an Incidentally Discovered Meningioma in a Patient With a History of Metastatic Prostate Cancer: A Case Report

Meningiomas are common, benign tumors found in the dural layers of central nervous system (CNS) that often incidentally. 18F-fluciclovine is an amino acid radiotracer used to monitor recurrence prostate cancer due its high uptake cells. This case report outlines a patient with retinoblastoma tumor suppressor gene (RB1) mutation and metastasis bone incidentally noted have enhancing, extra-axial mass on screening MRI. On prior scans, displayed increased uptake. Because can metastasize meninges, especially older patients advanced disease, consideration was given progression his oncological disease. However, additional imaging validated existence size mass, making meningioma final diagnosis. Meningeal metastases be virtually indistinguishable from other CNS tumors, including meningiomas appearing as single or multiple dural-based, enhancing masses, without imaging, further investigation warranted.